VH · Heavy chain variable region120 aa
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSPUBLIC ANTIBODY SEQUENCE · PSC-HER2-003
Trastuzumab antibody sequence
HER2 / CD340 · ERBB2
A core reference antibody for HER2 expression, internalization, competition and early ADC method development.
Public variable-region amino-acid sequences
The sequences below cover the VH and VL variable regions. They do not include the constant region, signal peptide or other engineered design selected for a customer project.
VL · Light chain variable region107 aa
DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKPUBLIC SOURCEThera-SAbDab PL132 · Approved (Feb 2025)
View the original Thera-SAbDab record Suggested research applications
- HER2 binding detection
- Internalization studies
- Flow cytometry
- ADC method development
Suggested starting labels
SF488SF594PEAPC
Dye selection can be adjusted for instrument lasers, co-expression intensity and panel design. Final selection is confirmed during project assessment.
Optional project scope
- Sequence review and construct design
- Recombinant expression and purification
- Fluorescent conjugation and free-dye removal
- Concentration, appearance and agreed basic quality checks
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Start a project from this public sequence
Submit the intended antibody format, scale, fluorophore and application. We will first confirm the technical route and delivery boundaries.