VH · Heavy chain variable region121 aa
QVQLQQSGSELKKPGASVKVSCKASGYTFTNYGMNWVKQAPGQGLKWMGWINTYTGEPTYTDDFKGRFAFSLDTSVSTAYLQISSLKADDTAVYFCARGGFGSSYWYFDVWGQGSLVTVSSPUBLIC ANTIBODY SEQUENCE · PSC-TROP2-010
Sacituzumab antibody sequence
TROP-2 · TACSTD2
A high-interest reference antibody for TROP-2-high tumors, internalization and early ADC development.
Public variable-region amino-acid sequences
The sequences below cover the VH and VL variable regions. They do not include the constant region, signal peptide or other engineered design selected for a customer project.
VL · Light chain variable region107 aa
DIQLTQSPSSLSASVGDRVSITCKASQDVSIAVAWYQQKPGKAPKLLIYSASYRYTGVPDRFSGSGSGTDFTLTISSLQPEDFAVYYCQQHYITPLTFGAGTKVEIKPUBLIC SOURCEThera-SAbDab PL132 · Approved / Active (Feb 2025)
View the original Thera-SAbDab record Suggested research applications
- TROP-2 binding detection
- Tumor-cell phenotyping
- Internalization studies
- ADC method development
Suggested starting labels
SF488SF594PEAPC
Dye selection can be adjusted for instrument lasers, co-expression intensity and panel design. Final selection is confirmed during project assessment.
Optional project scope
- Sequence review and construct design
- Recombinant expression and purification
- Fluorescent conjugation and free-dye removal
- Concentration, appearance and agreed basic quality checks
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Start a project from this public sequence
Submit the intended antibody format, scale, fluorophore and application. We will first confirm the technical route and delivery boundaries.