PUBLIC ANTIBODY SEQUENCE · PSC-PD1-001

Pembrolizumab antibody sequence

PD-1 / CD279 · PDCD1

A high-demand reference antibody for immune-checkpoint research and flow-based binding or competition assays.

PD-1CD279PDCD1Whole mAbIgG4
VARIABLE-REGION SEQUENCES

Public variable-region amino-acid sequences

The sequences below cover the VH and VL variable regions. They do not include the constant region, signal peptide or other engineered design selected for a customer project.

VH · Heavy chain variable region120 aa
QVQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSS
VL · Light chain variable region111 aa
EIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIK
PUBLIC SOURCEThera-SAbDab PL132 · Approved / Active (Feb 2025)
View the original Thera-SAbDab record
RESEARCH USE

Suggested research applications

  • PD-1 binding detection
  • Competitive blocking
  • Flow cytometry
  • Method control
FLUORESCENT OPTIONS

Suggested starting labels

SF488PEAPCUV421

Dye selection can be adjusted for instrument lasers, co-expression intensity and panel design. Final selection is confirmed during project assessment.

DELIVERABLE

Optional project scope

  • Sequence review and construct design
  • Recombinant expression and purification
  • Fluorescent conjugation and free-dye removal
  • Concentration, appearance and agreed basic quality checks
START FROM THIS SEQUENCE

Start a project from this public sequence

Submit the intended antibody format, scale, fluorophore and application. We will first confirm the technical route and delivery boundaries.

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Pembrolizumab Antibody Sequence (PD-1 / CD279) | VH/VL | StellaCyte