VH · Heavy chain variable region118 aa
QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYTMHWVRQAPGKGLEWVTFISYDGNNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAIYYCARTGWLGPFDYWGQGTLVTVSSPUBLIC ANTIBODY SEQUENCE · PSC-CTLA4-007
Ipilimumab antibody sequence
CTLA-4 / CD152 · CTLA4
A standard reference sequence for CTLA-4 checkpoint, activated T-cell and competitive-blocking studies.
Public variable-region amino-acid sequences
The sequences below cover the VH and VL variable regions. They do not include the constant region, signal peptide or other engineered design selected for a customer project.
VL · Light chain variable region108 aa
EIVLTQSPGTLSLSPGERATLSCRASQSVGSSYLAWYQQKPGQAPRLLIYGAFSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIKPUBLIC SOURCEThera-SAbDab PL132 · Approved / Active (Feb 2025)
View the original Thera-SAbDab record Suggested research applications
- CTLA-4 binding detection
- Competitive blocking
- T-cell phenotyping
- Flow cytometry
Suggested starting labels
UV421SF488PEAPC
Dye selection can be adjusted for instrument lasers, co-expression intensity and panel design. Final selection is confirmed during project assessment.
Optional project scope
- Sequence review and construct design
- Recombinant expression and purification
- Fluorescent conjugation and free-dye removal
- Concentration, appearance and agreed basic quality checks
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Start a project from this public sequence
Submit the intended antibody format, scale, fluorophore and application. We will first confirm the technical route and delivery boundaries.