PUBLIC ANTIBODY SEQUENCE · PSC-PDL1-002

Atezolizumab antibody sequence

PD-L1 / CD274 · CD274

A commonly used reference sequence for PD-L1 expression, receptor-occupancy and immune-checkpoint blockade research.

PD-L1CD274B7-H1Whole mAbIgG1
VARIABLE-REGION SEQUENCES

Public variable-region amino-acid sequences

The sequences below cover the VH and VL variable regions. They do not include the constant region, signal peptide or other engineered design selected for a customer project.

VH · Heavy chain variable region118 aa
EVQLVESGGGLVQPGGSLRLSCAASGFTFSDSWIHWVRQAPGKGLEWVAWISPYGGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARRHWPGGFDYWGQGTLVTVSS
VL · Light chain variable region107 aa
DIQMTQSPSSLSASVGDRVTITCRASQDVSTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYLYHPATFGQGTKVEIK
PUBLIC SOURCEThera-SAbDab PL132 · Approved / Active (Feb 2025)
View the original Thera-SAbDab record
RESEARCH USE

Suggested research applications

  • PD-L1 binding detection
  • Competitive blocking
  • Flow cytometry
  • Tumor-cell phenotyping
FLUORESCENT OPTIONS

Suggested starting labels

SF488SF594PEAPC

Dye selection can be adjusted for instrument lasers, co-expression intensity and panel design. Final selection is confirmed during project assessment.

DELIVERABLE

Optional project scope

  • Sequence review and construct design
  • Recombinant expression and purification
  • Fluorescent conjugation and free-dye removal
  • Concentration, appearance and agreed basic quality checks
START FROM THIS SEQUENCE

Start a project from this public sequence

Submit the intended antibody format, scale, fluorophore and application. We will first confirm the technical route and delivery boundaries.

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Atezolizumab Antibody Sequence (PD-L1 / CD274) | VH/VL | StellaCyte